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‘King Kong’ of weight-loss jabs helps dieters keep weight off for THREE years, scientists discover

Published on April 11, 2025 at 10:01 PM

THE ‘King Kong' of fat jabs could help dieters keep weight off for three years, a study has revealed.

Italian scientists discovered blasts fat for the long haul, with women seeing the most dramatic results.

Mounjaro (tirzepatide) injection pen and box.
Women taking Mounjaro lost, on average, a third of their body weight

In a trial of 700 blokes and women who were either or carried extra weight, half were given tirzepatide, the ingredient in Mounjaro, and half received a placebo.

After three years of using the jabs, those on the weekly weight-loss injection had shed up to 30 per cent of their body weight, compared to just 10 per cent in the placebo group.

The effects were particularly strong in women, who shed an average of 31 per cent of their body weight, while men lost an average of 26 per cent.

They also kept losing weight for longer, with 82.7 per cent hitting their weight plateau after 36 to 48 weeks, compared to 74.5 per cent of men who plateaued earlier.

And once they stopped losing, most kept the weight off – with 87 per cent staying at least 20 to 25 per cent down on their starting weight by the end of the study.

This suggests the jabs can continue working during long-term use.

Study author Dr Luca Busetto, from the University of Padova, said: “Our long-term analysis of tirzepatide establishes that clinically relevant weight loss can be sustained for up to three years in a diverse population of adults.”

The new research is being presented at this year’s European Congress on Obesity (ECO) in Malaga, Spain in May.

Previous studies have suggested Mounjaro is better for weight loss than semaglutide – the ingredient in weight loss jabs and .

All of them belong to a class of meds called GLP-1 receptor agonists.

They mimic gut hormones to slash appetite and slow digestion, making you feel fuller for longer.

Mounjaro is currently only given out on the NHS for patients with to help control blood sugar and encourage .

But new NICE guidelines will extend it to people with obesity and related health problems over the next three years.

To qualify, Brits will need a BMI over 35 and at least one weight-related condition like high blood pressure or diabetes.

But anyone with a BMI over 30 can already get it privately for around £150 a month.

Meanwhile, earlier the year, Flying Eze reported that after using weight-loss and diabetes jabs such as Ozempic and Mounjaro.

The official figures from the Medicines and Healthcare products Regulatory Agency reveal the toll up to the end of January.

The disclosure comes as awithout any checks.

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