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The Simpsons fans stunned as iconic twins Patty and Selma undergo shock ‘Ozempic transformation’ – and fans aren’t happy

Published on April 07, 2025 at 11:21 AM

THE Simpsons fans have been left stunned as the show's iconic twins Patty and Selma Bouvier have undergone a shock ‘Ozempic transformation' on the show.

The long-running animated sitcom has taken a look at the weight-loss jab which has taken the world by storm with both Patty and Selma ditching a tonne of weight by using a jab.

Illustration of Selma and Patty Bouvier, Marge Simpson's sisters, smoking.
Patty and Selma have ditched the weight thanks to Ozempic in a shock transformation
Illustration of Marge Simpson and her sisters, Patty and Selma, sitting on a couch watching TV.
In the latest episode, the pair were totally slimmed down
Illustration of a Simpsons character carrying a paint bucket.
Comic Book Guy also flaunted a new physique

They aren't the only ones who will be sporting a slimmed down appearance in the latest episode of the programme as Comic Book Guy, famed for wearing a T-shirt too small for his bulging belly, will also show off a new look thanks to the weight-loss apparatus.

In an episode aired last night, entitled The Last Man Expanding, fans saw how all three characters had managed to ditch the fat.

As the new craze hit Springfield, the characters were all left attempting to lose the pounds through their version of the drug, called “Othinquic”.

It left chain-smoking sisters Patty and Selma looking unrecognisable as they were left as thing as their other sister, Marge.

But despite already being petite herself, Marge was also left tempted to use the Ozempic-style drug after seeing how many of her neighbours, and family members, had transformed their bodies as a result.

One of the biggest transformations was the hugely overweight Comic Book Guy who looked unrecognisable after devouring “family-sized Othinquic”.

But some fans have been left unhappy by the decision for to go down the weight-loss route – particularly with Patty and Selma.

Writing online, one fan posted on X: “Can’t believe what Ozempic is doing to our beautiful queens.”

Another insisted: “They were already perfect.”

As a third shared: “I'm surprised Patty and Selma went in for it too…”

However, their slimmed down physique's are unlikely to stay for future episodes with most episode of The Simpsons reverting back to its original plot lines with each episode in order to keep it set within a linear universe.

New episodes of The Simpsons stream exclusively on Disney+ in the UK after leaving in in 20 years in January.

Fans of the programme have tuned in at 6:30pm for years to get their regularfix– but were left disappointed when it meant under a new UK deal, Channel 4 would no longer be screening the show.

However, terrestrial television will still get some Simpsons episodes, albeit a few series behind.

In January,E4became the only home of the show on linear TV with episodes from season 32 airing on the channel.

These episodes will then be made available to stream on Channel 4's online platform for a very limited time shortly after airing before being ultimately retained exclusively by Disney+.

Comic Book Guy from The Simpsons.
He was largely overweight
Illustration of the Simpsons family and friends watching TV.
The new episode aired as part of the show's latest series
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