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The common vitamins and supplements putting you at risk of stroke, brain and organ damage
The common vitamins and supplements putting you at risk of stroke, brain and organ damage
Published on March 25, 2025 at 01:28 PM
SUPPLEMENTS can help to keep us healthy.
Vitamin A helps fight off infections, calcium is vital for bones and teeth, and fish oil supports the heart, lungs and blood vessels, for example.
Supplements can trigger life-threatening conditions when taken in high doses, experts warn
But taking too much of any supplement can have serious consequences, experts warn.
Not only can overdosing cause nausea and vomiting, it's also been linked to an increased risk of stroke and organ damage.
Writing in The Conversation, Dipa Kamdar, senior lecturer in pharmacy practice at Kingston University, said: “Around half of UK adults currently take a food supplement.
“But vitamins and minerals are usually only needed in small amounts and too much of a good thing can be bad for you.”
Here are all the benefits and potential life-threatening risks of some of the most common vitamins and minerals.
Vitamin A
Vitamin A helps your body fight infection, as well as boost your vision in dim light and maintain healthy skin.
It's found in cheese, eggs, oily fish, milk and liver, but over-the-counter supplements are also widely available.
Men aged 19 to 64 need 700 micrograms (mg or µg) a day, while women need 600mg.
Some research suggests that taking more than 1,500mg of vitamin A every day for many years could make your bones more likely to fracture as you age.
“This is particularly important for older people, especially women, who are already at increased risk of osteoporosis, a condition that weakens bones,” the NHS says.
In severe cases, this can lead to irreversible liver damage, medics warn.
And be careful if you take other supplements like fish liver oil, as these are also high in vitamin A.
If you're pregnant, you should avoid vitamin A supplements and liver products altogether as they can harm your unborn baby.
Research published in the journal Nutrients found vitamin A could cause birth defects and miscarriage when taken in excess.
Vitamin B6
If you don't eat enough pork, poultry, peanuts, soya beans, oats or bananas, you may not be getting enough vitamin B6.
This could cause fatigue, skin rashes, cracked lips, a swollen tongue and even mood changes.
Dr Harry Jarrett, head of science and research at supplement brand Heights, previously told Flying Eze: “Low vitamin B6 levels have been linked to a greater risk of cardiovascular disease, certain cancers and depression and anxiety.”
But be careful not to take too much either.
“Taking 200mg or more a day of vitamin B6 can lead to a loss of feeling in the arms and legs known as peripheral neuropathy,” the NHS says.
“This will usually improve once you stop taking the supplements, but in a few cases when people have taken large amounts of vitamin B6, particularly for more than a few months, the effect can be permanent.”
Vitamin B6 helps the body to use and store energy from protein and carbohydrates in food, and the body form haemoglobin, the substance in red blood cells that carries oxygen around the body.
Men aged 19 to 64 need 1.4mg per day, while women need 1.2mg.
Most people can get all the vitamins and minerals they need from a balanced diet
It can also cause problems for people with hemochromatosis, or too much iron, as vitamin C is known to enhance iron absorption.
“This may lead to iron overload, which can cause serious damage to your heart, liver, pancreas, thyroid and central nervous system,” Healthline says.
Consuming too much vitamin C can also increase the amount of oxalate (waste product) in your urine, which hikes your risk of kidney stones.
In a study by the University of Texas Southwestern Medical Center, adults who took a 1,000mg supplement twice a day for six days increased their oxalate excretion by 20 per cent.
It's therefore recommended adults consume no more than 40mg a day.
Vitamin C is found in citrus fruits, peppers, strawberries, broccoli and potatoes.
Vitamin D and calcium
Vitamin D helps to regulate the amount of calcium and phosphate in the body.
These nutrients are needed to keep bones, teeth and muscles healthy, according to theNHS.
The body creates vitamin D from direct sunlight on theskinwhen outdoors, and during the spring and summer, most people should be able to make all the vitamin D they need naturally.
However, the NHS recommends taking a 10mg supplement between October and March, when daylight hours are shorter.
Adults and children over the age of one need 10mg of vitamin D a day. Babies under 12 months need 8.5 to 10mg.
Not getting enough vitamin D puts you at risk of bone deformities such asrickets,and bone pain known as osteomalacia.
But taking too much vitamin D over long periods can cause kidney failure and irregular heartbeats, scientists say.
A study by the University of Calgary also suggested that high doses could weaken bones.
“Do not take more than 100mg of vitamin D a day as it could be harmful,” the NHS says.
Vitamin D is found in a small number of foods, including oily fish, red meat, liver, egg yolks, and some fortified products like cereals.
Vitamin E
Avoid vitamin E toxicity by keeping your intake to 4mg for men and 3mg for women.
“There is not enough evidence to know what the effects might be of taking high doses of vitamin E supplements each day, but it could be harmful,” the NHS says.
Some studies have suggested excessive intake could cause blood thinning, clotting and potentially fatal bleeding.
It has also been linked to an increased risk of a stroke caused by bleeding in the brain.
Most people should be able to get all the vitamin E they need from their diet.
Good sources include olive oil, nuts and seeds, and wheatgerm.
Fish oil
Fish is packed full of vitamins and minerals, which is why the NHS recommends we eat at least two portions of the stuff every week.
Oily fish specifically – like herring, salmon and sardines – contains long-chain omega-3 fatty acids, which are said to help to prevent heart disease.
The benefits of fish oil seem to be best in people with existing heart problems.
The nasty ingredients hiding in supplements
Supplements can help us reach vitamin and mineral recommendations.
But Dr Carol Granger, a registered nutrition practitioner with a degree in biochemistry and a masters in microbiology, warns of many additions to supplements, medications and foods that could cause side effects, and suggests doing your research before buying commercial pills.
She tells Sun Health: “Ingredients like talc, E numbers, and gelatin are all used as bulking agents or as colourings and they can have serious long-term health impacts like heartburn, dizziness, fainting and severe allergic reactions.”
Here are the worst culprits:
Magnesium stearate
Unlike the name suggests, this ingredient contains no magnesium (which may help with sleep, anxiety and bone health).
Dr Granger says: “This is used as a lubricant – it prevents ingredients sticking together and means the machines that make the tablets don’t block.”;
But she warns that “high amounts can cause a laxative effect and it can cause inflammation too, especially in those who are sensitive to allergies”;.
It’s unlikely the small amount found in supplements is enough to do harm, but it may be worth reconsidering if you have been taking it for a long time.
Ascorbyl Palmitate
Ascorbyl palmitate is a form of vitamin C made by combining ascorbic and palmitic acids.
It’s considered safe in the amounts that are used when added to skincare.
Dr Granger says: “This is used as an antioxidant food additive and preservative meaning things with it in can have a longer use by date.”;
But she claims “excess amounts can cause nausea, diarrhoea, and vomiting”;.
Aspartame
You’ll may be familiar with aspartame, which is a sugar-alternative often used in things like soft drinks, sweetened diet products or other ‘low/no sugar’ foods.
Dr Granger says: “This is a sweetener a lot of people have heard of.
“It’s a flavour enhancer but because it’s an artificial sweetener, it has been linked to weight gain.”;
Studies have found both that sweeteners like aspartame help people lose weight, but also gain weight by potentially increasing appetite.
Several studies have linked high intakes to more serious health problems such as cardiovascular disease, cancer, and dementia but there has been much debate about the results.
But Dr Granger claims: “It can affect metabolism so if you see it on any ingredient list, my advice would be to give it a wide berth.”;
Carrageenans
Carrageenan is an ingredient that has long had concern surrounding it.
Products with it may be labelled as ‘natural’ because it is derived from seaweed, therefore it is also found in some plant-based/vegan foods.
But Dr Granger says: “The processing used to make some types of carrageenan makes it into something you definitely don’t want to consume.
“They’re widely used as gelling agent and thickener. They can be used to prevent powder clumping so may be in powder supplements you add to smoothies.
“But some cause inflammation, are really bad for digestive health and have been linked to ulcers too.
“Some can also destabilise blood sugar and cause problems with blood sugar balance.”;
Calcium Phosphate
Calcium phosphate is a mineral (calcium and phosphate) which are essential for bone, muscle, blood and nerve health.
Some may benefit from additional calcium, such as menopausal women with weakening bones.
But calcium phosphate is also used as an additive to products, from supplements to toothpaste and fertilizers.
Dr Granger says: “This is used to bulk out and buffer ingredients like vitamin C.
“Side effects can include kidney problems, loss of appetite and weakness.”;
Folic acid
Folic acid is the synthetic version of the vitamin folate, also known as vitamin B9.
It helps the body to make healthy red blood cells and is found in foods like leafy green vegetables, chickpeas and fortified cereals.
Supplements (400mg) are usually recommended before pregnancy and during the first 12 weeks to prevent defects like spina bifida, when a baby's spine and spinal cord does not develop properly in the womb.
Higher doses are not thought to be harmful, but taking more than 1,000mg could mask symptoms of vitamin B12 deficiency.
This can make you feel tired, as well as cause headaches, indigestion, weakness, palpitations and a sore or red tongue.
Some people also experience neurological symptoms like depression, anxiety, problems with balance and coordination, pins and needles and muscle weakness.
The NHS says: “It's important forvitamin B12 or folate deficiency anaemia to be diagnosed and treated as soon as possible.
“Although many of the symptoms improve with treatment, some problems caused by the condition can be irreversible if left untreated.
“The longer the condition goes untreated, the higher the chance of permanent damage.”
Iodine
Taking high doses of iodine for long periods could change the way your thyroid gland works.
This can have several knock-on effects, including weight gain.
Limit your intake to 140mg a day, in line with NHS recommendations.
Most people should be able to get all the iodine they need by eating a varied and balanced diet.
Good sources include dairy, eggs, fish and some fortified plant-based drinks.
Iron
How much iron you need will depend on several factors.
But generally the NHS recommends 8.7mg a day for men aged 19 and over, 8.7mg for women 50 and over, and 14.8mg for women 19 to 49.
Sticking to these guidelines helps make red blood cells, which carry oxygen around the body.
But taking iron in high doses (over 20mg) can trigger constipation, nausea, vomiting, stomach pain and potentially liver failure, the NHS and NIH warn.
“Very high doses of iron can be fatal, particularly if taken by children, so always keep iron supplements out of the reach of children,” the health service adds.
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