A WOMAN felt -like she was being “ripped open by a knife”; after suffering extreme reaction to a single weight loss jab.
Karen Coe, 59, decided to try the injections to lose weight and help combat type two , and was prescribed them on the NHS.


But after her first injection of the jab on March 14 she began to get a and feel dizzy.
Three days later on March 17, she woke up at 5am with “excruciating”; , suffered with extreme and had to get her husband, Rob, 59, to call for an ambulance.
Karen – who only injected herself once – was told to go home and keep an eye on her symptoms.
She spent the next 24 hours with stomach cramps and passing blood when she went to the toilet.
Karen’s symptoms eased off but she once again rushed to A&E when she passed “massive blood clots”; on March 24.
After an examination, she was urgently referred to see a colorectal surgeon.
Doctors said her initial symptoms were likely caused by Mounjaro, she claims.
The NHS lists nausea, diarrhoea and abdominal cramps as potential .
The doctors haven’t confirmed the cause of her recent complications.
Now she wants to warn others of the potential reactions to the weight loss jab – after it was revealed that .
Karen, an activities co-ordinator, from Hailsham, East , said: “At first I had a headache and got dizzy.
“I had a few stomach cramps.
“On Monday it was excruciating. It was like being ripped open with a knife.”;
Karen said she had previously tried metformin to treat her diabetes but had struggled with diarrhoea.



After hearing success stories from friends about Mounjaro she spoke to her diabetic nurse and was prescribed the injections.
She said she was made aware of possible side effects – which include nausea, diarrhoea and stomach discomfort – but didn’t know she would have such an extreme reaction.
Karen said: “I nearly passed out.
“I had to ask my husband to call for an ambulance.
“I was dizzy and really cold.
“They did my observations and said it was all OK.”;
Karen was told to keep an eye on her symptoms – which have now started to get better – but she has been left weak and unable to eat.
She said: “Every few minutes I would go to the loo and pass blood.”;
Karen won’t be continuing with her Mounjaro injections.
She said: “It can cause severe reactions and severe side effects.
“People should really think carefully and don’t take it lightly.”;
Eli Lilly – who make Mounjaro, or tirzepatide – said: “Patient safety is Lilly’s top priority.
“We take any reports regarding patient safety extremely seriously and actively monitor, evaluate, and report safety information for all our medicines.
“The Mounjaro (tirzepatide) Patient Information Leaflet warns that various gastrointestinal side effects – including nausea, diarrhoea, vomiting, stomach pain, and constipation – are common or very common side effects.
“We encourage patients to consult their doctor or other healthcare professional regarding any side effects they may be experiencing and to ensure that they are getting genuine Lilly medicine.”;